These might old issues. I read the guide about setting retreat on Medium so I am trying that without any cheats.
-- When an artifact becomes available for pickup, a little graphic issue will appear.
-- Vehicles will surround an incomplete repair facility. They should ignore them until they are built.
-- I have the standard 500 MB videos installed. After the second completed mission and hitting a key to skip the videos. The game will usually crash with an orange screen after the last the video and just before returning to the game.
-- Retreat on medium damnage doesn't seem to stick. After a vehicle is repaired or at the start of a new mission, you need to reset it. You also can't assign a default "retreat" indicator on new vehicles.
FYI
Specs:
Windows 7 64-bit
AMD ATI driver 10.10 HD 5400
9 GB RAM
Running at 1920 by 1600.